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- $Unique_ID{BRK00462}
- $Pretitle{}
- $Title{Information on "Progressive Supranuclear Palsy"}
- $Subject{palsy brain supranuclear Ill Defined Symptoms symptom slowness
- imbalance falling impaired vision aged elder elderly geriatric old older age
- vertical gaze expressionless face slurred forced speech nerves degeneration
- apathy dementia dopaminergic anticholinergic antiserotonic}
- $Volume{N-1}
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- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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- Information on "Progressive Supranuclear Palsy"
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- QUESTION: My father-in-law has been diagnosed as having "progressive
- supranuclear palsy"--a very frustrating and heart wrecking disease to watch
- happen to a once healthy and virile man. Although family members have
- searched for information on this disease, we have found none. What can you
- tell us and what can we expect?
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- ANSWER: This is an uncommon disease that affects men twice as often as women.
- It usually begins with complaints of slowness of movement, imbalance and
- falling, and impaired vision, and strikes in patients in the 60 to 70 year age
- range. They note difficulty in negotiating steps and curbs, and marked
- problems in looking upward or down. It is this problem with vertical gaze
- that leads physicians to the diagnosis for it is the hallmark of the disease.
- As the name indicates the disease is progressive, and leads to difficulty in
- moving and turning, an expressionless face, slurred and forced speech
- patterns. Though there are no specific laboratory tests available that help
- in making the diagnosis, the appearance of the patient and the slow
- progression of the clinical symptoms and signs leave little doubt of its
- identity. We know that it damages the nerves in the brain, but have no idea
- of the cause of this degeneration. The disease progresses steadily over a six
- to eight year period, and mental changes of apathy and dementia may occur late
- in the course of the affliction. Trials of treatment have left much to be
- desired although three classes of medication, dopaminergic, anticholinergic or
- antiserotonic drugs have been reported to help some patients. I am sorry I
- don't have more hopeful information to give you.
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- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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